Evaluation of a caprine arthritis-encephalitis virus/maedi-visna virus indirect enzyme-linked immunosorbent assay in the serological diagnosis of ovine progressive pneumonia virus in U.S. sheep.
نویسندگان
چکیده
A caprine arthritis-encephalitis virus (CAEV)/maedi-visna virus (MVV) indirect enzyme-linked immunosorbent assay (iELISA) was validated with samples from U.S. sheep and by the use of radioimmunoprecipitation as the standard for comparison. The sensitivity and the specificity were 86.0% (+ or - 5.8%) and 95.9% (+ or - 2.9%), respectively. The iELISA format and phylogenetic differences based on the MVV gag sequence contribute to the reduced sensitivity.
منابع مشابه
Evaluation of five enzyme-linked immunosorbent assays and an agar gel immunodiffusion test for detection of antibodies to small ruminant lentiviruses.
In the framework of the Dutch control program for small ruminant lentiviral (SRLV) infections, too many drawbacks were encountered with respect to serological testing. To improve the quality of testing, five enzyme-linked immunosorbent assays (ELISAs) and an agar gel immunodiffusion test (AGIDT) were evaluated. The focus was on the sensitivity, specificity, and variances of the commercially ava...
متن کاملCaprine Arthritis and Encephalitis
Caprine arthritis and encephalitis (CAE) is an economically important viral disease of goats. The caprine arthritis encephalitis virus (CAEV), a lentivirus; infects its hosts for life. Although most infections are subclinical, a minority of animals develops progressive, untreatable disease syndromes including polyarthritis in adults and encephalomyelitis in kids. This virus also causes indurati...
متن کاملCaprine Arthritis and Encephalitis
Caprine arthritis and encephalitis (CAE) is an economically important viral disease of goats. The caprine arthritis encephalitis virus (CAEV), a lentivirus; infects its hosts for life. Although most infections are subclinical, a minority of animals develops progressive, untreatable disease syndromes including polyarthritis in adults and encephalomyelitis in kids. This virus also causes indurati...
متن کاملMorphological and immunological comparison of caprine arthritis encephalitis and ovine progressive pneumonia viruses.
Caprine arthritis encephalitis virus (CAEV) causes a variety of pathological conditions ranging from mild to very severe and from acute to chronic, depending upon the age of initial infection and other variables. Although the virus has been reported to have properties of characteristic of retroviruses and to be related to maedi-visna virus (also called progressive pneumonia virus [PPV]), relati...
متن کاملCaprine Arthritis-Encephalitis, Small Ruminant Lentivius Infection
Importance Caprine arthritis and encephalitis (CAE) is an economically important viral disease of goats. The caprine arthritis encephalitis virus (CAEV), a lentivirus; infects its hosts for life. Although most infections are subclinical, a minority of animals develops progressive, untreatable disease syndromes including polyarthritis in adults and encephalomyelitis in kids. This virus also caus...
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ورودعنوان ژورنال:
- Clinical and vaccine immunology : CVI
دوره 17 2 شماره
صفحات -
تاریخ انتشار 2010